i. Summary

MD candidate at the University of Münster, working at the intersection of cancer biology, molecular medicine, and clinical care.

Pursuing additional research training in Experimental Medicine alongside the medical curriculum. Previously a Visiting Student Researcher in Hani Goodarzi's lab at UCSF (Boehringer Ingelheim Fonds MD fellowship), studying RNA-binding proteins in breast cancer and designing and executing CRISPR-based functional screens related to metastasis biology.

Wet-lab methods include cell culture, molecular cloning, PCR, single-cell RNA-seq, and RNA-seq library preparation.

ii. Education

  1. Apr 2019
    May 2027
    Westfälische Wilhelms-Universität Münster
    Doctor of Medicine — State Exam in Medicine
    • First State Exam (M1, 2021): grade 1 — within the top 1% of students.
    • Second State Exam (M2, 2025): grade 1 — within the top 1% of students.
    • USMLE Step 1: Pass (2024). USMLE Step 2 CK: 273.
    • Currently in the final clinical year (Praktisches Jahr) and Experimental Medicine training.

iii. Research experience

  1. Apr 2022
    Sep 2023
    UCSF — Goodarzi Lab
    Visiting Student Researcher · San Francisco
    • RNA-binding proteins (RBPs) and their role in breast cancer progression and metastasis.
    • Designed and executed multiple CRISPRi functional screens to investigate RBP function.
    • Cell culture, molecular cloning, PCR, single-cell RNA-seq, RNA-seq library preparation.
    • Funded by the Boehringer Ingelheim Fonds MD fellowship.

iv. Publications

  1. Integrative analysis of mRNA stability regulation uncovers a metastasis-suppressive program in breast cancer
    H. Karner†, T. C. Mittmann†, et al.
    Science Advances 12, eaea9061 · 2026 · peer reviewed · † co-first authors
  2. A generative framework for enhanced cell-type specificity in rationally designed mRNAs
    M. Khoroshkin, A. Zinkevich, E. Aristova, H. Yousefi, S. B. Lee, T. Mittmann, K. Manegold, D. Penzar, D. R. Raleigh, I. V. Kulakovskiy, H. Goodarzi
    bioRxiv doi:10.1101/2024.12.31.630783 · 2024 · preprint

v. Fellowships & honors

  • 2023
    2026
    Studienstiftung des Deutschen Volkes
    Fellowship of the German National Academic Foundation — three-year award.
  • 2022
    2023
    Boehringer Ingelheim Fonds MD Fellowship
    Seventeen-month fellowship supporting research at the Goodarzi Lab, UCSF.
  • 2025
    Second State Exam in Medicine — grade 1 (top 1%)
    Westfälische Wilhelms-Universität Münster.
  • 2021
    First State Exam in Medicine — grade 1 (top 1%)
    Westfälische Wilhelms-Universität Münster.

vi. Teaching & service

  1. 2021
    Biochemistry Laboratory Course Tutor
    University of Münster
    • Instruction and guidance of students in biochemistry wet-lab protocols.
  2. 2020
    2022
    Anatomy & Imaging Course Tutor
    University of Münster
    • Assisted students in learning and understanding human anatomy and anatomical imaging.
  3. 2020
    2021
    MeDocs — IT Support for Lecturers
    University of Münster
    • Provided technical support for online lectures during the COVID-19 pandemic.

vii. Methods & skills

Wet lab. Mammalian cell culture; molecular cloning; PCR; CRISPRi functional screens; lentiviral vector handling; single-cell RNA-seq and RNA-seq library preparation.

Topics. Cancer biology · molecular biology · translational research · RNA-binding proteins · breast cancer metastasis · mRNA stability.

Clinical training. Full preclinical and clinical curriculum of the University of Münster MD program; final-year clinical rotations (Praktisches Jahr); USMLE Step 1 and Step 2 CK passed.

viii. Languages

  • Germannative (Muttersprache)
  • Englishfluent — TOEFL 115
  • Frenchfluent — DELF B2